Following the immunization program economic evaluation standards set by the World Health Organization, this study aims to construct Markov transition models, SEIR models, and other disease burden models. It will compare the health and economic outcomes between implementing and not implementing the National Immunization Program (NIP) in China. The research will analyze 15 birth cohorts from 2008 to 2022. The study includes five routine childhood NIP vaccines: four doses of DTP, four doses of polio vaccine, two doses of measles-containing vaccine, three doses of hepatitis B vaccine, and one/two doses of hepatitis A vaccine. The analysis will utilize vaccine coverage data provided by the Chinese Center for Disease Control and Prevention from 2008 to 2022. The study aims to calculate the input and output of China’s NIP.
1) Evaluate the cost and effectiveness of China’s National Immunization Program for children over the past 15 years (2008-2022);
2) Conduct an economic evaluation of China’s National Immunization Program (vaccines) from a societal perspective.
The epidemiological data, treatment costs, vaccine coverage data, and other relevant information for measles, hepatitis A, and hepatitis B have been collected.