{"id":8778,"date":"2023-02-18T14:38:33","date_gmt":"2023-02-18T06:38:33","guid":{"rendered":"https:\/\/vaxlab.dukekunshan.edu.cn\/paper\/current-status-challenges-and-recommendations-of-pneumococcal-conjugate-vaccine\/"},"modified":"2025-06-28T11:24:00","modified_gmt":"2025-06-28T03:24:00","slug":"current-status-challenges-and-recommendations-of-pneumococcal-conjugate-vaccine","status":"publish","type":"paper","link":"https:\/\/vaxlab.dukekunshan.edu.cn\/en\/paper\/current-status-challenges-and-recommendations-of-pneumococcal-conjugate-vaccine\/","title":{"rendered":"Current Status, Challenges and Recommendations of Pneumococcal Conjugate Vaccine"},"content":{"rendered":"\n

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\u4e3a\u63a8\u8fdbPCV\u75ab\u82d7\u5728\u6211\u56fd\u513f\u7ae5\u4e2d\u7684\u4f7f\u7528\uff0c\u63d0\u9ad8\u75ab\u82d7\u8986\u76d6\u7387\uff0c\u5efa\u8bae\uff1a<\/p>\n\n

\u4e00\u662f\u5206\u9636\u6bb5\u5c06PCV\u7eb3\u5165\u56fd\u5bb6\u514d\u75ab\u89c4\u5212\u3002<\/strong>\u8fd9\u662f\u63d0\u5347\u6211\u56fd\u513f\u7ae5\u5065\u5eb7\u6c34\u5e73\u3001\u964d\u4f4e\u80ba\u708e\u94fe\u7403\u83cc\u76f8\u5173\u75be\u75c5\u8d1f\u62c5\u7684\u91cd\u8981\u624b\u6bb5\uff0c\u5728\u5c11\u5b50\u5316\u80cc\u666f\u4e0b\u5c24\u4e3a\u91cd\u8981\uff0c\u4e14\u6709\u52a9\u4e8e\u63d0\u5347\u6b20\u53d1\u8fbe\u5730\u533a\u75ab\u82d7\u63a5\u79cd\u6c34\u5e73\uff0c\u964d\u4f4e\u5730\u533a\u95f4\u7684\u5065\u5eb7\u4e0d\u516c\u5e73\uff0c\u7b26\u5408\u6211\u56fd\u624e\u5b9e\u63a8\u8fdb\u5171\u540c\u5bcc\u88d5\u7684\u653f\u7b56\u76ee\u6807\u3002\u5c3d\u7ba1\u5f53\u524dPCV\u4ef7\u683c\u8f83\u9ad8\uff0c\u4f46\u5168\u56fd\u5c42\u9762\u7eb3\u5165\u514d\u75ab\u89c4\u5212\u540e\uff0c\u5de8\u5927\u7684\u9700\u6c42\u91cf\u3001\u56fd\u4ea7\u75ab\u82d7\u4e0a\u5e02\u540e\u7ade\u4e89\u6027\u683c\u5c40\u7684\u51fa\u73b0\uff0c\u4f7f\u6211\u56fd\u5177\u5907\u4ee5\u5e9e\u5927\u5e02\u573a\u6362\u53d6\u66f4\u4f4e\u4ef7\u683c\u7684\u7a7a\u95f4\u3002<\/strong>\u53ef\u501f\u9274\u56fd\u9645\u793e\u4f1a\u7684\u6210\u529f\u7ecf\u9a8c\uff0c\u4e00\u662f\u9009\u62e9\u591a\u5382\u5bb6\u96c6\u4e2d\u91c7\u8d2d\u4ee5\u91cf\u6362\u4ef7\uff0c\u8fbe\u5230\u901a\u8fc7\u4ef7\u683c\u8c08\u5224\u5927\u5e45\u5ea6\u964d\u4f4e\u75ab\u82d7\u91c7\u8d2d\u4ef7\u683c\u7684\u76ee\u6807\uff0c\u4e8c\u662f\u501f\u9274GAVI\u7684\u75ab\u82d7\u9884\u5148\u5e02\u573a\u627f\u8bfa\u8ba1\u5212\uff0c\u63d0\u524d\u4e09\u5230\u4e94\u5e74\u4e0e\u56fd\u5185\u75ab\u82d7\u4f01\u4e1a\u6c9f\u901a\u62db\u6807\uff0c\u5efa\u7acb\u957f\u671f\u91c7\u8d2d\u8ba2\u5355\uff0c\u5e2e\u52a9\u4f01\u4e1a\u964d\u4f4e\u751f\u4ea7\u53ca\u6269\u4ea7\u6210\u672c\uff0c\u964d\u4f4e\u91c7\u8d2d\u4ef7\u683c\u3002\u82e5\u76f4\u63a5\u7eb3\u5165\u7684\u6761\u4ef6\u5c1a\u4e0d\u6210\u719f\uff0c\u53ef\u4ee5\u8003\u8651\uff1a<\/p>\n\n

1. \u7ecf\u6d4e\u53d1\u8fbe\u7701\u5e02\u5148\u884c\u63a2\u7d22\u5c06PCV\u7eb3\u5165\u5730\u65b9\u514d\u75ab\u89c4\u5212\u3002<\/strong>\u56fd\u5185\u90e8\u5206\u7701\u5e02\u3001\u533a\u53bf\u7684\u8d22\u653f\u538b\u529b\u8f83\u8f7b\uff0c\u4f8b\u5982\u5317\u4eac\u3001\u4e0a\u6d77\u7b49\u57ce\u5e02\uff0c\u53ef\u4ee5\u4f5c\u4e3a\u8bd5\u70b9\u5148\u884c\u5c06PCV\u6309\u7167\u514d\u75ab\u89c4\u5212\u75ab\u82d7\u7ba1\u7406\uff0c\u514d\u8d39\u4e3a\u9002\u9f84\u513f\u7ae5\u63a5\u79cd\uff0c\u4e3aPCV\u7eb3\u5165\u56fd\u5bb6\u514d\u75ab\u89c4\u5212\u63d0\u4f9b\u66f4\u52a0\u5145\u5206\u7684\u8bc1\u636e\u3002\u82e5\u6682\u65f6\u4e0d\u6ee1\u8db3\u7eb3\u5165\u514d\u75ab\u89c4\u5212\u7684\u6761\u4ef6\uff0c\u53ef\u4ee5\u8003\u8651\u5206\u6b65\u5b9e\u65bd\uff0c\u5148\u5c06\u90e8\u5206\u5242\u6b21\u7eb3\u5165\u514d\u8d39\u63a5\u79cd\u3002\u4f8b\u5982\u5c71\u4e1c\u6f4d\u574a\u5df2\u7ecf\u4f5c\u4e3a\u8bd5\u70b9\u5f00\u5c55\u4e86\u4e00\u5242\u6b21\u514d\u8d39\u7684\u6a21\u5f0f\u63a2\u7d22\uff0c\u5168\u5e026\u6708\u9f84\u4ee5\u4e0a2\u5468\u5c81\u4ee5\u5185\u513f\u7ae5\u4e0d\u8bba\u65e2\u5f80\u662f\u5426\u63a5\u79cd\u8fc7\u80ba\u708e\u75ab\u82d7\uff0c\u5747\u53ef\u514d\u8d39\u63a5\u79cd\u4e00\u5242\u6b21PCV13\u3002\u5efa\u8bae\u603b\u7ed3\u63a8\u5e7f\u5730\u65b9\u7ecf\u9a8c\uff0c\u5c3d\u5feb\u6269\u5927\u8986\u76d6\u8303\u56f4\u3002<\/p>\n\n

2. \u52a0\u5927\u5bf9\u4f4e\u6536\u5165\u4eba\u7fa4\u548c\u6b20\u53d1\u8fbe\u5730\u533a\u7684\u652f\u6301\u529b\u5ea6\u3002<\/strong>\u5982\u524d\u6240\u8ff0\uff0c\u8d8a\u662f\u7ecf\u6d4e\u6b20\u53d1\u8fbe\u7684\u5730\u533a\u80ba\u708e\u94fe\u7403\u83cc\u6027\u75be\u75c5\u7684\u53d1\u751f\u7387\u548c\u6b7b\u4ea1\u7387\u8d8a\u9ad8\uff0c\u4f46\u7531\u4e8e\u7ecf\u6d4e\u6761\u4ef6\u7684\u9650\u5236\u8fd9\u4e9b\u5730\u533a\u75ab\u82d7\u7684\u53ef\u53ca\u6027\u66f4\u5dee\uff0c\u4f4e\u6536\u5165\u7fa4\u4f53\u53d7\u5230\u80ba\u708e\u94fe\u7403\u83cc\u76f8\u5173\u75be\u75c5\u7684\u51b2\u51fb\u4e5f\u66f4\u5927\u3002\u8fd9\u90e8\u5206\u7fa4\u4f53\u66f4\u9700\u8981\u516c\u5171\u8d44\u91d1\u548c\u793e\u4f1a\u8d44\u6e90\u7684\u652f\u6301\u3002\u5efa\u8bae\u501f\u9274HPV\u75ab\u82d7\u63a8\u5e7f\u7684\u7ecf\u9a8c\uff0c\u5728\u75be\u75c5\u8d1f\u62c5\u8f83\u91cd\u7684\u5730\u533a\u63a2\u7d22\u4f01\u4e1a\u6350\u52a9\u914d\u5408\u8d22\u653f\u652f\u6301\u7684\u6a21\u5f0f\uff0c\u52a0\u5927\u653f\u5e9c\u8d44\u91d1\u6295\u5165\u529b\u5ea6\uff0c\u4f18\u5148\u5c06\u8d44\u6e90\u503e\u659c\u7ed9\u897f\u90e8\u5730\u533a\uff0c\u5229\u7528\u653f\u5e9c\u6c11\u751f\u9879\u76ee\u548c\u533b\u4fdd\u57fa\u91d1\u591a\u6e20\u9053\u7b79\u8d44\uff0c\u518d\u52a0\u4e0a\u4e00\u5b9a\u6bd4\u4f8b\u7684\u4e2a\u4eba\u652f\u4ed8\uff0c\u4e3a\u4f4e\u6536\u5165\u7fa4\u4f53\u63d0\u4f9b\u8865\u8d34\uff0c\u5148\u4fdd\u8bc1\u75ab\u82d7\u5728\u4e00\u5b9a\u533a\u57df\u3001\u4e00\u5b9a\u4eba\u7fa4\u5185\u7684\u5e94\u7528\uff0c\u518d\u9010\u6b65\u63a8\u5e7f\u5230\u66f4\u5927\u8303\u56f4\u3002<\/p>\n\n

3. \u6b64\u5916\u4e5f\u53ef\u4ee5\u8003\u8651\u5efa\u7acb\u591a\u5143\u7b79\u8d44\u673a\u5236\uff0c\u5f62\u6210\u5408\u7406\u8d39\u7528\u5206\u62c5\u3002<\/strong>\u4f8b\u5982\u5c1d\u8bd5\u63a2\u7d22\u5c06\u75ab\u82d7\u63a5\u79cd\u8d39\u7528\u7eb3\u5165\u533b\u4fdd\u62a5\u9500\u8303\u56f4\uff0c\u5141\u8bb8\u533b\u4fdd\u4e2a\u4eba\u8d26\u6237\u652f\u4ed8\uff0c\u51cf\u5c11\u5bb6\u5ead\u81ea\u4ed8\u652f\u51fa\u7684\u6bd4\u4f8b\uff1b\u9f13\u52b1\u5546\u4e1a\u5065\u5eb7\u9669\u5f00\u53d1\u8986\u76d6PCV\u75ab\u82d7\u7684\u4ea7\u54c1\uff0c\u66f4\u597d\u53d1\u6325\u5546\u4e1a\u5065\u5eb7\u4fdd\u9669\u7684\u4f5c\u7528\u3002<\/p>\n\n

\u4e8c\u662f\u9f13\u52b1\u56fd\u5185\u75ab\u82d7\u751f\u4ea7\u5382\u5546\u7814\u53d1\u9ad8\u4ef7\u6b21PCV\u75ab\u82d7\uff0c\u62d3\u5c55\u63a5\u79cd\u5e74\u9f84\u8303\u56f4\uff0c\u63d0\u9ad8PCV\u4ea7\u80fd\uff0c\u79ef\u6781\u53c2\u4e0e\u5e02\u573a\u7ade\u4e89\u3002<\/strong>\u81ea2020\u5e745\u6708\u5f00\u59cb\uff0c\u56fd\u4ea7\u7684PCV\u5df2\u7ecf\u542f\u52a8\u63a5\u79cd\u3002\u5728\u575a\u6301\u79d1\u5b66\u6027\u3001\u786e\u4fdd\u5b89\u5168\u6027\u7684\u57fa\u7840\u4e0a\uff0c\u901a\u8fc7\u7a0e\u6536\u3001\u8865\u8d34\u3001\u5e73\u53f0\u5efa\u8bbe\u7b49\u653f\u7b56\u624b\u6bb5\uff0c\u9f13\u52b1\u56fd\u5185\u4f01\u4e1a\u52a0\u5feb\u75ab\u82d7\u7814\u53d1\u8fdb\u5ea6\uff0c\u964d\u4f4e\u63a5\u79cd\u6210\u672c\uff0c\u5e76\u53ca\u65f6\u5e94\u5bf9\u80ba\u708e\u94fe\u7403\u83cc\u6d41\u884c\u53d8\u5316\uff0c\u8ddf\u8e2a\u7814\u53d1\u9ad8\u4ef7\u6b21\u75ab\u82d7\u3002\u9f13\u52b1\u4f01\u4e1a\u8fdb\u4e00\u6b65\u589e\u52a0\u75ab\u82d7\u7814\u53d1\u548c\u4ea7\u4e1a\u5316\u6295\u5165\uff0c\u79ef\u6781\u6269\u5927\u75ab\u82d7\u4ea7\u80fd\uff0c\u5b9e\u73b0\u75ab\u82d7\u751f\u4ea7\u89c4\u6a21\u5316\u3001\u96c6\u7ea6\u5316\uff0c\u4fdd\u8bc1\u7a33\u5b9a\u751f\u4ea7\u4f9b\u5e94\uff0c\u63d0\u5347PCV\u63a5\u79cd\u53ef\u53ca\u6027\u548c\u516c\u5e73\u6027\u3002<\/p>\n\n

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Streptococcus pneumoniae is a commonly carried bacterium in the nasopharynx of Chinese children and can lead to serious health conditions such as pneumonia, meningitis, and lifelong sequelae. The diseases caused by this bacterium not only harm children, but also place a significant economic burden on families.<\/p>\n","protected":false},"featured_media":8777,"menu_order":1,"template":"","format":"standard","meta":{"type_label":"none_selected"},"paper-tag":[],"class_list":["post-8778","paper","type-paper","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/vaxlab.dukekunshan.edu.cn\/en\/wp-json\/wp\/v2\/paper\/8778","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vaxlab.dukekunshan.edu.cn\/en\/wp-json\/wp\/v2\/paper"}],"about":[{"href":"https:\/\/vaxlab.dukekunshan.edu.cn\/en\/wp-json\/wp\/v2\/types\/paper"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vaxlab.dukekunshan.edu.cn\/en\/wp-json\/wp\/v2\/media\/8777"}],"wp:attachment":[{"href":"https:\/\/vaxlab.dukekunshan.edu.cn\/en\/wp-json\/wp\/v2\/media?parent=8778"}],"wp:term":[{"taxonomy":"paper-tag","embeddable":true,"href":"https:\/\/vaxlab.dukekunshan.edu.cn\/en\/wp-json\/wp\/v2\/paper-tag?post=8778"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}